翟红林 (教授)★

翟红林教授(Prof. H. L. Zhai)，男，博士生导师。1964年出生，1986年6月兰州大学化学系物理化学本科专业毕业获学士学位并留校工作至今。2004年12月获兰州大学分析化学博士学位，2007年1月至2008年1月赴台湾长庚大学分子医学研究中心开展抗癌药物设计及癌症早期诊断的博士后研究工作。专业特长为数据建模与分析、程序设计与应用；目前主要从事复杂体系中的多组分同时定性与定量分析、实验条件优化、药物分子与蛋白质相互作用模拟、药物分子设计及计算机技术在化学等相关领域应用的教学与科研工作。已在Analyst、Analytica Chimica Acta、Food Chemistry、J. Chromatography A、Talanta、J. Separation Science、J. Chemical Information and Modeling、Chemometrics and Intelligent Laboratory Systems、Chemical Biology & Drug Design、Computational Biology & Chemistry等国内外学术期刊上发表研究论文六十余篇；已主持并完成国家自然科学基金面上项目及多项校企横向课题。

近期发表的代表性论文：

1.      Chemical image moments and their applications. TrAC-Trends in Analytical Chemistry, 2018, 103: 119-125.

2.      Molecular modeling study on resistance of WT/D473H SMO to antagonists LDE-225 and LEQ-506. Pharmacological Research, 2018, 129: 491-499.

3.      An effective approach to quantitative analysis of ternary amino acids in foxtail millet substrate based on Terahertz Spectroscopy. Food Chemistry, 2018, 246: 220-227.

4.      Prediction of phosphorylation sites based on Krawtchouk image moments. PROTEINS: Structure, Function, and Bioinformatics, 2017, 85: 2231-2238.

5.      Exploring the binding mechanism of Heteroaryldihydropyrimidines and Hepatitis B Virus capsid combined 3D-QSAR and molecular dynamics. Antiviral Research, 2017, 137: 151-164.

6.      Krawtchouk image moment method for the simultaneous determination of three drugs in human plasma based on fluorescence three-dimensional spectra. Talanta, 2016, 161: 99-104.

7.      An approach to the quantitative analysis of multiple components based on liquid chromatography mass spectrometry in full scan mode. Journal of Separation Science, 2016, 39(15): 3054-3061.

8.      The determination of multi-components utilizing ¹H NMR three-dimensional spectra combined Tchebichef moments. Chemometrics and Intelligent Laboratory Systems, 2016, 156: 128-136.

9.      Study on the active mechanism of β-secretase inhibitors by molecular simulations. European Journal of pharmaceutical sciences, 2015, 76: 138-148.

10.  The application of Tchebichef moment method on the quantitative analysis of multiple compounds based on three-dimensional HPLC fingerprint spectra. Analyst, 2015, 140(2): 630-636.