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谢志翔 (教授)★

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姓  名
谢志翔
所属部门
有机化学第三研究所
职  称
教授
导师类别
博士生导师
研究方向
合成有机化学
联系方式

    谢志翔教授 (Professor Zhixiang Xie),博士生导师。1996年毕业于广西大学化工系,无机化工专业;19961999年兰州大学化学系从事天然产物的分离和结构鉴定;19992002年bet365提现要多久师从李瀛教授,从事天然产物全合成。2002年~2004年师从北京大学有机合成化学家杨震教授从事博士后研究。20047月作为引进人才到兰州大学工作,2012年入选教育部新世纪优秀人才支持计划20129月~20133月作为高级研究学者在Stanford大学访学,合作导师Barry M. Trost。谢志翔教授长期从事有机化学教学和科研工作,主讲有机化学课程,参与《有机化学》教材编写,曾主讲本科生及研究生有机立体化学、研究生有机合成专论等课程;主持国家自然科学基金四项、教育部博士点基金一项,作为骨干成员参与973项目一项;主持多项药物合成开发纵向项目。迄今已在Angew. Chem., Org. Lett., J. Org. Chem., Chem-Eur J.等国际刊物上发表学术论文40余篇。

    研究领域与研究方向:

    1. 具有抗艾滋病活性的天然产物不对称合成研究

    2. 天然产物仿生合成及合成方法学研究

    3. 药物合成工艺开发

近期发表代表性论文目录:

1.     Yong Wang, Yuhan Zhang, Zhongle Li, Zhenjie Yang and Zhixiang Xie*. "A highly efficient synthesis of the DEFG-ring system of rubriflordilactone B", Org. Chem. Fron., 2017, 4, 47 – 51.

2.     Yuhan Zhang, Yonghong Guo, Zhongle Li, and Zhixiang Xie*. “Biomimetic Total Synthesis of Paeoveitol”, Org. Lett. 2016, 18, 4578?4581.

3.     Yong Wang, Zhongle Li, Liangbo Lv, Zhixiang Xie*. “Synthetic Study of Rubriflordilactone B: Highly Stereoselective Construction of the C-5-epi ABCDE Ring System”, Org. Lett. 2016, 18, 792-795.

4.     Zhou, Nini; Li, Zhongle; Xie, Zhixiang*. “Synthesis of α-Enamino Esters via Cu(II)-promoted Dehydrogenation of α-Amino Acid Esters: Application to Synthesis of Polysubstituted Pyrroles” Org. Chem. Fron., 2015, 2, 1521 – 1530.

5.     Nini Zhou, Tao Xie, Zhongle Li, and Zhixiang Xie*, “Cu(II)/TEMPO Promoted One-Pot Synthesis of Highly Substituted Pyrimidines from Amino Acid Esters”, Chem. Eur. J., 2014, 20(52), 17311-17314.

6.     Nini Zhou, Tao Xie, Lin Liu, and Zhixiang Xie*, “Cu/Mn Co-oxidized Cyclization for the Synthesis of Highly Substituted Pyrrole Derivatives from Amino Acid Esters: A Strategy for the Biomimetic Syntheses of Lycogarubin C and Chromopyrrolic Acid”, J. Org. Chem. 2014, 79 (13), 6061–6068. (Highlighted in Synfacts 2014, 10, 0914)

7.     Hong-Ru Dong, Wang-Jun Dong, Rong-Shan Li, Yi-Ming Hu, Heng-Shan Dong* and Zhi-Xiang Xie* “Synthesis of β-cyanopropan-1-one derivates by domino reaction”, Green Chem., 2014, 16, 3454–3457.

8.     Lin Wei, Mingxing Xiao, Zhixiang Xie*, “Total Syntheses of (?)-Spirooliganones A and B” Org. Lett. 2014, 16 (10), 2784–2786. (Highlighted in Synfacts 2014, 10, 1009)

9.     Mingxing Xiao, Lin Wei, Liqi Li, and Zhixiang Xie*, “Total Synthesis of (±)-Przewalskin B” J. Org. Chem. 2014, 79 (6), 2746–2750.

10.    Wei Wu, Mingxing Xiao, Jiangbing Wang, Ying Li, and Zhixiang Xie*, “Biomimetic Total Synthesis of (-)-Isatisine A”, Org. Lett. 2012, 14, 1624-1627.

11.    Yingying Wu, Chao Du, Congcong Hu, Ying Li, and Zhixiang Xie*, “Biomimetic Synthesis of Hyperolactones”, J. Org. Chem. 2011, 76 (10), 4075–4081.

12.    Du, Chao; Li, Li-Qi; Li, Ying; Xie, Zhi-Xiang*; “Construction of Two Vicinal Quaternary Carbons by Asymmetric Allylic Alkylation: Total Synthesis of Hyperolactone C and (-)-Biyouyanagin A”, Angew. Chem. Int. Ed. 2009, 48, 7853-7856.