涂永强(院士)★
涂永强,1958年出生,理学博士,教授,博士生导师,中国科学院院士。1982年、1985年和1989年在兰州大学分别获得学士、硕士和博士学位,1993年至1995年在澳大利亚昆士兰大学作博士后研究员。1996年入选国家“百千万人才工程”,2000年获国家杰出青年基金资助,2001年获首批国家自然科学基金委“有机化学创新群体”基金并任学术带头人且获得连续三期资助,2004年10月至2005年4月在德国比勒费尔德大学作访问教授,2004年受聘教育部“长江学者特聘教授”,2009年当选为中国科学院院士。曾任兰州大学化学系副主任、功能有机分子化学国家重点实验室主任、兰州大学有机化学研究所所长、教育部科技委委员。现任甘肃省化学会理事长、英国皇家化学会著名期刊《Chem. Commun.》副主编、《J. Org. Chem.》等期刊顾问编委,并兼任上海交通大学致远讲席教授。
涂永强教授主要从事复杂结构天然有机化合物的全合成及合成方法研究。在国内外重要学术刊物Chem. Rev.、Chem. Soc. Rev.、Acc. Chem. Res.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nat.Commun.等上发表论文200余篇,发明专利5项。主持国家科技部“973”项目子课题、国家自然科学基金委重大、重点、国际合作项目以及国家外专局和教育部联合资助的“药物化学”创新引智等多项科研项目。1992年获“中国化学会优秀青年化学奖”,1993年获“国家教委科技进步二等奖”,2000年获香求是科技基金会“杰出青年学者奖”,2002年获“甘肃省科技进步一等奖”,2005年获美国Lilly公司“杰出科研成就奖”,2006年获“甘肃省自然科学一等奖”,2012年获“全国优秀科技工作者”,2015年获“教育部自然科学一等奖”。
代表性论著:
1. Total Syntheses of the Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, and Conidiogenone?B. Angew. Chem. Int. Ed. 2016, 55, 4456.
2. Radical aryl migration reactions and synthetic applications. Chem. Soc. Rev.2015, 44, 5220.
3. Tandem C-H oxidation/cyclization/rearrangement and its application to asymmetric syntheses of (-)-brussonol and (-)-przewalskine E. Nat. Commun.2015, 6,7332.
4. Organocatalytic Asymmetric Tandem Nazarov Cyclization/Semipinacol Rearrangement: Rapid Construction of Chiral Spiro[4.4]nonane-1,6-diones. J. Am. Chem. Soc. 2015, 137, 8344.
5. Divergent and Efficient Syntheses of the Lycopodium Alkaloids (-)-Lycojaponicumin C, (-)-8-Deoxyserratinine, (+)-Fawcettimine, and (+)-Fawcettidine. Angew. Chem. Int. Ed.2013, 52, 11373.
6. Copper-Catalyzed Tandem Trifluoromethylation/Semipinacol Rearrangement of Allylic Alcohols. Angew. Chem. Int. Ed.2013, 52, 9781.
7. Total Synthesis of the Nominal Didemnaketal A. Angew. Chem. Int. Ed.2012, 51, 10846.
8. Organocatalytic Asymmetric Direct Csp3-H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers. Angew. Chem. Int. Ed.2012, 51, 8811.
9. Total Synthesis of (+/-)-Alopecuridine and Its Biomimetic Transformation into (+/-)-Sieboldine A. Angew. Chem. Int. Ed.2011, 50, 3916.
10. Direct Sp3 alpha-C-H activation and functionalization of alcohol and ether.Chem. Soc. Rev.2011, 40, 1937.
11. Stereoselective Construction of Quaternary Carbon Stereocenters via a Semipinacol Rearrangement Strategy. Acc. Chem. Res.2011, 44, 1207.
12. Semipinacol Rearrangement in Natural Product Synthesis. Chem. Rev.2011, 111, 7523.
13. Organocatalytic Asymmetric Halogenation/Semipinacol Rearrangement: Highly Efficient Synthesis of Chiral alpha-Oxa-Quaternary beta-Haloketones. J. Am. Chem. Soc.2011, 133, 8818.
14. Iron-Catalyzed C(sp(3))-C(sp(3)) Bond Formation through C(sp(3))-H Functionalization: A Cross-Coupling Reaction of Alcohols with Alkenes. Angew. Chem. Int. Ed.2009, 48, 8761.
15. Bronsted Acid Catalyzed Enantioselective Semipinacol Rearrangement for the Synthesis of Chiral Spiroethers. Angew. Chem. Int. Ed.2009, 48, 8572.
16. Organocatalytic Asymmetric Vinylogous alpha-Ketol Rearrangement: Enantioselective Construction of Chiral All-Carbon Quaternary Stereocenters in Spirocyclic Diketones via Semipinacol-Type 1,2-Carbon Migration. J. Am. Chem. Soc.2009, 131, 14626.
17. A reaction for sp(3)-sp(3) C-C bond formation via cooperation of Lewis acid-promoted/Rh-catalyzed C-H bond activation. J. Am. Chem. Soc.2005, 127, 10836.
18. A tandem semipinacol rearrangement/alkylation of alpha-epoxy alcohols: An efficient and stereoselective approach to multifunctional 1,3-diols. Angew. Chem. Int. Ed.2004, 43, 1702.
19. Samarium-catalyzed tandem semipinacol rearrangement/Tishchenko reaction of alpha-hydroxy epoxides: A novel approach to highly stereoselective construction of 2-quaternary 1,3-diol units. Angew. Chem. Int. Ed.2001, 40, 3877.